Name: Akihiko Yoshimura
Date of Birth: 12/12/58
Place of Birth: Saga, Japan
Home address:
2-7-2 Komorino-machi, Kurume 830-0001 Japan
Business address:
Education:
Undergraduate: 1976-1980 Kyoto University, Kyoto, Japan
Biology and Chemistry B.S. awarded 3/80
Graduate: 1980-1985 Kyoto University, Kyoto, Japan
Department of Biophysics Ph.D. awarded 3/86
Research Appointment:
1985-1987 Assistant Professor, Oita Medical School, Oita, Japan
1987-1989 Assistant Professor, Cancer Research Institute, Kagoshima University, Kagoshima, Japan
1989-1991 Postdoctoral Research Fellow, Whitehead Institute for Biomedical Research, Cambridge, MA, USA
1989-1995 Associate Professor, Cancer Research Institute, Kagoshima University, Kagoshima, Japan
1995-2000 Professor, Insutitute of Life Science, Kurume University, Kurume, Japan
2001-2007 Professor, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
2008- Professor, Keio University School of Medicine
Award
Japan Biochemistry Society Award 2007 Mochida Memorial award 2007
Japan Immunology Society Award 2001
Reaserch
Cytokines are polypeptide hormones that mainly regulate hematopoiesis and immune system, and induce growth, differentiation and functional changes of cells. Cytokines are essential for homeostasis and defense against infectious diseases through immunoregulation. Therefore, disorders of cytokine functions are strongly related to autoimmune and inflammatory diseases. However, regulatory mechanism of signaling of cytokines remains to be investigated. We have found the CIS/SOCS family and the Sprouty/Spred family, which are deeply involved in the regulation of immune system and hematopoiesis. Furthermore, we also found that these genes are involved in cancer, inflammation, obesity and allergy. We are trying to uncover the molecular mechanism of cytokine signaling regulation as well as its relationship to diseases.
 Yoshimura-lab members |
 TOP |
 publications |